This does happen. SAEs are reported in real time, and they do halt trials sometimes. Also, there is often a condition of approval that requires ongoing data collection for adverse events post-approval.
I can say in one role in my job, I'm getting a lot of use and I know my colleagues are at least trying a lot of things. One use is a first-pass review of animal care and use protocols. The Claude project was given all of the relevant policies and guidelines as well as a fairly long prompt that explains the things we look for in protocol review. It's checking some things that the software we use makes very tedious to check and raising inconsistencies between sections. Some places have a full time "protocol reader" who does this kind of first check, but we've never had that, so it's helpful.
Another project I'm seeing in the same realm is taking an approved protocol and some study results and checking that the records of what was done match what they said they could do in the approved protocol. It can also make sure that surgical records have all the things they should have. This can help meet one of the requirements from the national accreditation organization to do "post approval monitoring".
Another way I've used it is to have it collate and compare a particular kind of policy across many institutions who transparently put their policies online. Seeing the commonality between the policies and where some excel helped me rewrite our policy.
This is work that just wasn't happening before or, more accurately, it was being spread over lots of people, and any improvement in efficiency or consistency is hard to measure.
Frequently, two movies with very similar concepts drop the same year. Is that because they're spying, or because the companies make decisions in similar ways based on similar input information?
Transparently, I'm not a designer, I'm a biologist. That said, the things I want designed by Claude don't need great design. I need a slide format that is consistent from one study to the next so the reader can follow. I need a tool that tracks the number of mice in each lab and flags if someone is using more resources than we expect. I need a personal site that is easy to work with that tracks my pet geckos' feed and environment.
If I have a product out of my lab that makes it to human trials, there will be a full team of marketers and designers tasked to the brand image.
I doubt you’d be singing the same tune if Anthropic released Claude Researcher and a bunch of people were saying “I’m a designer, not a biologist. I don’t need great research. I just need X”
Ironically I think AI will replace researchers before it replaces artists.
I'm not the one saying my job is uniquely human. Last week, I watched a video of a vendor's new facility that entirely automates antibody production and screening lab. The machines run literally every step from picking antibodies, sequencing, scaling up, and in vitro screening without a human interfering or donning a labcoat. A machine that is essentially a nicer roomba fetches the flask and drives it to where the shakers are and puts it on an empty shaker spot. I have no doubt the lab tasks I do can be automated. Fortunately for me, a large portion of my job at the moment is in handling animals, and there are much higher barriers there, but again, I don't think that part of my job makes me irreplaceable.
Yeah, looks like the KALLAX is preferred, the BILLY does leave a bit of album hanging out. (Although I don't believe you need all of 13" for an album sleeve—perhaps closer to 12½". Still overhang though.)
In practice, the entities who gave money directly to the US government are the ones who paid the tariff. Those entities should be pressured to refund the consumers, but in practice, that's unlikely.
I (unknowingly) ordered something on Etsy from another country. UPS delivered the items, then sent me a letter requiring I pay the tariff and an extra tariff handling fee. UPS paid the government, so UPS should get their money back from the government, then refund me. I'm not holding my breath.
Economically it is a direct redistribution of wealth. In crisis times, Congress acts swiftly to cure wrongs against corporations. What about this wrong against every single household?
UPS is definitely pocketing most of whatever refund they get. And golly gee gosh what a shocker, the company supports Republicans. I'm afraid you've been robbed.
> ‘Corporate and industry group political action committees have donated more than $44 million directly to the campaigns and leadership PACs of the 147 members of the Sedition Caucus. Companies and trade associations that pledged to suspend donations have given more than $12 million to the campaign and leadership PACs of the Sedition Caucus.
> Koch Industries ($626,500), American Crystal Sugar ($530,000), Home Depot ($525,000), Boeing ($488,000), and UPS ($479,500) have contributed the most money to members of the Sedition Caucus through their corporate PACs.’
> Tomé’s reconciliation with representatives who legitimized Trump’s attempted presidential coup — and who may control Congress after the November midterm elections — shouldn’t surprise us. Trump lavished huge gifts on UPS and Corporate America that have made them richer.”
> The second Trump presidency has the potential to be even more lucrative for UPS, given that the bulk of UPS’s unionized workers are Teamsters and led by prominent Trump ally Sean O’Brien
> UPS is definitely pocketing most of whatever refund they get. And golly gee gosh what a shocker, the company supports Republicans. I'm afraid you've been robbed.
Looks like they've given a pretty similar amount to both parties[1]. UPS charging a specific "Tariff Fee" is bound to have angered Trump.
This is an inherent problem with storing power. There's a massive battery in Missouri known as the Taum Sauk hydroelectric dam. During the night, they pump water up the hill into the upper reservoir, and in the day, they let the water run downhill through turbines to generate electricity. In 2005, the wall of the upper reservoir failed.
This is great data visualization of interesting data! I'm curious about the last graph; there seems to be something making some of the longest flights take more time/nm. Is that real or an artifact, and is there an explanation for the tail?
Great question! It is not an anomaly, it is very geographically specific.
Due the the Ukraine war (and my home base being in the UK), we have to fly the long way around to get to far-east destinations like Tokyo and Hong Kong. Flying outbound from London we have to fly down over Turkey (which adds about two hours of flight time).
Flying home from Tokyo with the ongoing airspace closure, if the the weather is suitable at the ETOPS airports enroute, it is actually quicker to fly home eastbound again, flying up over Alaska. A proper around-the-world in 4 days!
So for London-Tokyo the return route is completely different from the outbound route? Fascinating! I guess that has something to do with the jetstream (which only helps you when travelling eastbound)?
reply